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RNDr. Ján Kozempel, Ph.D.

Present position
Head of Radiopharmaceutical chemistry unit at the Faculty of Nuclear Sciences and Physical Engineering Czech Technical University in Prague.
- Own laboratory start-up, new research team establishment.
- Research in the field of targeted alpha-particle therapy and modern diagnostic agents for PET/SPECT.


2010 Ph.D. in Organic Chemistry, Faculty of Sciences, Charles University in Prague, Czech Republic. Dissertation: Preparation of 64Cu and its prospective carriers for nuclear medicine, supervisor doc. RNDr. Ladislav Lešetický, CSc.
2005 Marie-Curie fellowship in the Joint Research Centre, EC, Ispra, Italy. Topic: Preparation and separation of 64Cu.
2004 RNDr. in nuclear chemistry, Faculty of Sciences, Charles University in Prague, Czech Republic.
2003 Mgr. (MSc) in Nuclear Chemistry, Faculty of Sciences, Charles University in Prague, Thesis: Study of iodine isotope exchange in aromatic compounds, supervisor doc. RNDr. Ladislav Lešetický, CSc.

Main Research Areas
Radiopharmaceutical Chemistry, Applied Nuclear Physics, Nuclear Chemistry, Nanotechnology

Publication Activities

Autor or co-author of more than 20 publications in international peer-reviewed journals. Number of citations (WoS, without self-citations): 185

Selected Publications: H Index 8 (Web of Science)

1. Simonelli, F; Marmorato, P; Abbas, K; Ponti, J; Kozempel, J; Holzwarth, U; Franchini, F; Rossi, F.: Cyclotron Production of Radioactive CeO2 Nanoparticles and Their Application for In Vitro Uptake Studies. IEEE TNB 10, 1, 44-50 (2011).
2. Gibson, N; Holzwarth, U; Abbas, K; Simonelli, F; Kozempel, J; Cydzik, I; Cotogno, G; Bulgheroni, A; Gilliland, D; Ponti, J; Franchini, F; Marmorato, P; Stamm, H; Kreyling, W; Wenk, A; Semmler-Behnke, M; Buono, S; Maciocco, L; Burgio, N.: Radiolabelling of engineered nanoparticles for in vitro and in vivo tracing applications using cyclotron accelerators. Arch Tox 85, 7, 751-773 (2011).
3. Marmorato, P; Simonelli, F; Abbas, K; Kozempel, J; Holzwarth, U; Franchini, F; Ponti, J; Gibson, N; Rossi, F.: Co-56-labelled radioactive Fe3O4 nanoparticles for in vitro uptake studies on Balb/3T3 and Caco-2 cell lines. J NANOPART RES 13, 12, 6707-6716 (2011).
4. Kozempel, J; Abbas, K; Simonelli, F; Bulgheroni, A; Holzwarth, U; Gibson, N.: Preparation of Cu-67 via deuteron irradiation of Zn-70. Radiochim Acta 100, 7, 419-423 (2012).
5. Moeller, W; Gibson, N; Geiser, M; Pokhrel, S; Wenk, A; Takenaka, S; Schmid, O; Bulgheroni, A; Simonelli, F; Kozempel, J; Holzwarth, U; Wigge, Ch; Eigeldinger-Berthou, S; Maedler, L; Kreyling, W. G.: Gold nanoparticle aerosols for rodent inhalation and translocation studies. J NANOPART RES 15, 4, 1574 (2013).
6. Holzwarth, U; Bellido, E; Dalmiglio, M; Kozempel, J; Cotogno, G; Gibson, N.: Be-7-recoil radiolabelling of industrially manufactured silica nanoparticles. J NANOPART RES 16, 9, 2574 (2014).
7. Kozempel, J; Vlk, M.: Nanoconstructs in Targeted Alpha-Therapy. Rec Pat Nanomed 4, 2, 71-76 (2014).
8. Kozempel, J; Vlk, Floriánová, M; Drtinová, B; Němec, M.: Dissolution of [226Ra]BaSO4 as part of a method for recovery of 226Ra from aged radium sources. J Radioanal Nucl Chem, DOI:10.1007/s10967-014-3433-2 (2015).
9. Kozempel, J; Vlk, M; Málková, E; Bajzíková, A; Bárta, J; Santos-Oliveira, R; Malta Rossi A.: Prospective carriers of 223Ra for targeted alpha particle therapy. J Radioanal Nucl Chem, DOI:10.1007/s10967-014-3615-y (2015).
10. Kukleva, E; Kozempel, J; Vlk, M., Mičolová, P; Vopálka, D.: Preparation of 227Ac/223Ra by neutron irradiation of 226Ra. J Radioanal Nucl Chem, DOI:10.1007/s10967-014-3432-3 (2015).